Diagnostic value of 99TcmO4-quantitative dynamic salivary gland imaging for primary ;Sj?gren’s syndrome / 中国医学装备

ABSTRACT

Objective: To investigate the diagnostic value of salivary gland scintigraphy for primary Sj?gren’s syndrome (pSS). Methods:This study took 50 pSS patients and 50 healthy women as the control group. All of them were performed salivary gland scintigraphy. We observed the imaging of salivary gland scintigraphy for two groups, and evaluated their salivary gland function. Results: In 50 patients with pSS, eight patients (16.0%) of bilateral parotid and submandibular glands were functioned well. While the function of bilateral parotid function and/or bilateral submandibular gland were observed reduction in other patients with pSS. The uptaking function decreased obviously in the typical patients with pSS, who are with bilateral parotid and submandibular glands. The uptake of 99TcmO4-was decreased in salivary glands, and the uptake of the oral cavity was lessened. After taken vitamin C tablets, there was no obvious concentration of 99TcmO4-. The time-radioactive type curve has continued to rise. The UR, S/T, SR and V of pSS patients were significantly lower than the control group, and the differences were statistically significant (P<0.01). Conclusion: Salivary gland scintigraphy is a non-invasive diagnosis with high-value for primary Sj?gren’s syndrome patients.