Childhood obesity and vitamin D deficiency / 国际儿科学杂志

ABSTRACT

Obesity and vitamin D deficiency have become two public health problems in children.In the past few decades,there has been increasing concern that low circulating levels of serum 25 (OH) D are associated with obesity and other metabolic diseases linked.However,the causal relationship between vitamin D deficiency and obesity is still unclear.There is currently insufficient evidence of beneficial effect to recommend vitamin D supplementation as a means of improving body weight,BMI or fat mass.Obesity probably leads to lower 25 (OH) D starus,while vitamin D and VDR are considered to have the ability to regulate energy balance through acting on adipogenesis,adipocyte apoptosis,lipogenesis and lipolysis,feeding behavior,and energy expenditure.