Research progress of microRNA in neuroblastoma / 国际儿科学杂志

ABSTRACT

Neuroblastoma is the most common extracranial malignant tumor in childhood.Tumor metastasis or relapse is one of the major causes of death in patients with neuroblastoma.The genesis of neuroblastoma is closely related to the embryonic development abnormal.However, the exact mechanism of pathogenesis, differentiation and metastasis still remain unclear.MicroRNA plays an important role in embryonic development and malignance pathogenesis, which is involved in the development and prognosis of tumor.This review summarizes the relationship between microRNA and neuroblastoma.