Analysis of Drug Resistance Characteristics of Imipenem-resistant Pseudomonas aeruginosa and Infection Risk Factors in Zhoushan Area / 中国药房
China Pharmacy
; (12): 1061-1063, 2016.
Article
Dans Zh
| WPRIM
| ID: wpr-501355
Responsable en Bibliothèque :
WPRO
ABSTRACT
OBJECTIVE:To provide reference for imipenem-resistant Pseudomonas aeruginosa infection control. METHODS:114 patients infected with imipenem-resistant P. aeruginosa were selected from 3 tertiary hospitals in Zhoushan during Feb. 2013 to Feb. 2014. 114 strains of P. aeruginosa were isolated from clinical specimens,and drug resistance characteristics and carbapene-mase-producing gene diversity were analyzed. 101 inpatients with imipenem-resistant P. aeruginosa infection were included in con-trol group;univariate and multivariate Logistic regression analysis were adopted to explore the risk factors of imipenem-resistant P. aeruginosa infection. RESULTS:114 strains were sensitive to polymyxin B,and had different levels of resistance to other 9 kinds of antibiotics. Carbapenemase-producing gene were mainly IMP and VIM type gene. Long-term hospitalization,mechanical ventila-tion,used imipenem and early combined use of antibiotics were risk factors of imipenem-resistant P. aeruginosa infection. CON-CLUSIONS:In Zhoushan area,imipenem-resistant P. aeruginosa shows serious drug resistance. To avoid long-term hospitalization and early combined use of antibiotics can reduce imipenem-resistant P. aeruginosa infection.
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Etiology_studies
/
Risk_factors_studies
langue:
Zh
Texte intégral:
China Pharmacy
Année:
2016
Type:
Article