Clinical Observation of Compound Glycyrrhizin Combination with Acyclovir in the Treatment of Children with Infectious Mononucleosis / 中国药房
China Pharmacy
;
(12): 5080-5082, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-501361
ABSTRACT
OBJECTIVE:
To observe the clinical efficacy and safety of compound glycyrrhizin combined with acyclovir in the treatment of children with infectious mononucleosis.METHODS:
90 children with infectious mononucleosis were randomly divid-ed into control group and research group. Control group was given Acyclovir injection 10 mg/(kg·d)adding into 150 ml 5% Glu-cose solution by intravenous infusion,twice a day. Research group was additionally given Compound glycyrrhizin injection 2-4 ml/kg,adding into 150 ml 5% Glucose solution by intravenous infusion,twice a day. The treatment course for both group was 2 weeks. Clinical efficacy,hospitalization time,improvement time of clinical symptoms,T lymphocyte subsets(CD3+,CD4+,CD8+ and CD4+/CD8+)before and after treatment and incidence of adverse reactions in 2 groups were observed.RESULTS:
The total effective rate in research group was significantly higher than control group,hospitalization time and improvement time of clinical symptoms were significantly better than control group,the differences were statistically significant(P0.05).CONCLUSIONS:
Compound glycyrrhizin combined with acyclovir has better efficacy than only acyclovir in the treatment of children with infectious mononucleosis,with similar safety.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
China Pharmacy
Année:
2015
Type:
Article
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