Effect Evaluation of Prophylactic Application of Antibiotics in Cardiothoracic Surgery before and after Clini-cal Pharmacist Intervention / 中国药房
China Pharmacy
;
(12): 3720-3722, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-502631
ABSTRACT
OBJECTIVE:
To investigate the effect of clinical pharmacist intervention on prophylactic application of antibiotics in cardiothoracic surgery.METHODS:
Medical records of patients underwent cardiothoracic surgery were collected from our hospi-tal during Mar. to Apr. in 2014 (before intervention) and during Jun. to Jul. in 2014 (after intervention). Those were divided into pre-intervention group(n=115)and post-intervention group(n=119). The prophylactic application effect of antibiotics was com-pared before and after intervention.RESULTS:
After intervention,the rates of prophylactic application were decreased significantly from 96.5% to 72.3%;the rationality rate of antibiotics selection was improved significantly from 27.9% to 94.2%;The course of prophylactic medication decreased significantly from(5.4±2.8)days to(2.3±1.8)days;the difference had statistical significance before and after intervention(P<0.01). The postoperative infection rate was decreased from 13.0% to 5.9%,the difference had no statistical significance(P=0.074). The average hospitalization time,average drug costs,and average hospitalization expenses were decreased significantly,the difference had statistical significance(P<0.05 or P<0.01).CONCLUSIONS:
Clinical pharmacist inter-vention to prophylactic application of antibiotics in cardiothoracic surgery can control the infection effective and guarantee reason-able and safe use of drugs during perioperative period.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
China Pharmacy
Année:
2015
Type:
Article
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