Impact of three different concentration of heparin tube -sealing solution on the jugular vein integrated catheter in hemodialysis patients / 中国基层医药

ABSTRACT

Objective To observe the impact of three different concentration heparin tube -sealing solution on the jugular vein integrated catheter in hemodialysis(HD)patients.Methods 96 HD patients were selected and divided into three groups according to different treatments.Each group had 32 cases.Patients in A,B and C group received heparin sodium 30mg,40mg,60mg respectively.The degree of symptoms improvement and the complications in the three groups were evaluated.Results For bleeding,catheter position adverse,arrhythmia,air embolism, A group had 10 cases,11 cases,8 cases,5 cases;B group had 9 cases,8 cases,9 cases,4 cases;C group had 2 cases, 1 case,1 case,0 case.Compared with B group and A group,C group had lower complication,the difference was statis-tically significant(χ2 =6.667,10.42,4.706 and 5.450,4.706,7.680,all P 0.05);For the infection and throm-bosis,A group had 10 cases,8 cases;B group had 9 cases,8 cases;C group had 1 case,1 case.Compared with B group and A group,C group had lower complication,the difference was statistically significant (χ2 =7.680,4.706,all P 0.05 ). Conclusion Treatment with 60mg heparin saline solution for HD patients will help to improve symptoms in patients, and decrease complications,thus it is worth for further promotion in clinical practice.