Evaluation of Measurement Uncertainty for the Content of Bisacodyl Enteric-coated Tablet by HPLC / 中国药房
China Pharmacy
;
(12): 3428-3430, 2016.
Article
Dans Chinois
| WPRIM
| ID: wpr-504928
ABSTRACT
OBJECTIVE:
To a evaluation method for the measurement uncertainty for the content of Bisacodyl enteric-coated tablet.METHODS:
HPLC external standard method was conducted for content determination of Bisacodyl enteric-coated tablet, and mathematical model for uncertainty evaluation was established to systematically analyze and evaluate the influential factors in processes of solution preparation and instrument measurement.RESULTS:
HPLC external standard method showed the content was 97.8%,confidence probability was 95%,expanded uncertainty was 2.8%,and determination result was (97.8 ± 2.8)%,k=2.CONCLUSIONS:
The established method is suitable for the evaluation of measurement uncertainty for the content of Bisacodyl en-teric-coated tablet. Regularly calibrated verification for HPLC equipment and strict control of the weighing process will help to im-prove the accuracy measured by HPLC.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Étude pronostique
langue:
Chinois
Texte intégral:
China Pharmacy
Année:
2016
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS