Research Progress of Ozone Oxidation and Ischemia-reperfusion Injury (review) / 中国康复理论与实践

ABSTRACT

As an active oxygen, ozone can induce oxidative stress, however, small doses of ozone pretreatment of the body may devel-op to oxidation toleration, even anti-oxidative damage, thereby protecting organ from ischemia-reperfusion injury. This paper reviewed the status of ozone pretreatment in organ ischemia-reperfusion, such as heart, kidney, liver, skeletal muscle, gonads and brain. Ozone therapy may have potential application values in organ transplants and cardiovascular diseases. Meanwhile, whether clinical application of ozone big autohemotherapy in ischemic cerebrovascular disease is reasonable or not in nearly 10 years was put forward.