Exosomes and leukemia / 国际儿科学杂志

ABSTRACT

Exosome is a type of nanosized membrane microvesicle that contains bioactive constituents and signal molecules.Exosomes have been shown to be released by the cells in vivo.Leukemia cell-derived exosomes were found in the plasma of leukemia patients and supernatant of leukemia cells after centrifuge.Leukemia cell-derived exosomes and Technology Development Program of Medicine can transfer leukemia-associated antigens and mieroRNA to target cells.Not only does it affect the development of leukemia,but it is also closely related to the treatment and prognosis of leukemia.