Research progress of microRNA in the development of the pancreas and type 1 diabetes / 中国糖尿病杂志

ABSTRACT

[Summary] The pathogenesis of type 1 diabetes has not been thoroughly understood. MicroRNA is a kind of small molecule RNA in regulating gene expression at post-transcriptional level. The dysfunction and amount changes of microRNA involve in the regulation of pancreaticβcell volume and function,and thus are related to type 1 diabetes. Here,we reviewed the research advances of microRNA in the development of the pancreas,insulin secretion and type 1 diabetes.