Effect of low-dose cefuroxime combined with dexamethasone on postoperative urinary tract infection and quality of life in cervical cancer patients / 中国生化药物杂志

ABSTRACT

Objective To investigate the effect of low-dose of cefuroxime combined with dexamethasone on postoperative urinary tract infection and quality of life in cervical cancer.Methods 90 cases of cervical cancer patients from July 2015 to July 2016 in the first affiliated hospital of wenzhou medical university were selected and divided into two groups,44 patients in control group received cefuroxime sodium 1.5 g and metronidazole 0.5 g biw in five days,furacilin 250 mL bladder irrigation biw after five days,and fourteenth days out of indwelling catheter.46 cases in the experiment group received more with cefuroxime 125 mg and dexamethasone 0.75 mg oral,and two groups were treated for 14 days.Results After treatment,the incidence rate of urinary tract infection rate,the first urination time>three hours and residual urine ≥100 mL in the experiment group were lower than the control group (P<0.05);the total effective rate of the experiment group was significantly higher than the control group (P <0.05);the scores of physical function,physical life, mental health and social adaptation in the experiment group were significantly higher than the control group ( P <0.05 ) . Conclusion Low dose cefuroxime combined with dexamethasone have better prevention effect on urinary tract infection after cervical cancer operation , can significantly improve the quality of life of patients and treatment efficiency.