Advances in differential roles of HIF-1αand HIF-2αin the pathogenesis of hypoxic pulmonary hypertension / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 10-13, 2017.
Article
Dans Chinois
| WPRIM
| ID: wpr-509262
ABSTRACT
Hypoxia-induced factors(HIFs)are the main regula-tors for the response of hypoxic environment.They are involved in hypoxia-related lung tissue cell damage and abnormal cell pro-liferation,among which,HIF-1αand HIF-2αplay the most im-prominant roles.This paper reviews the current researches of HIF-1αand HIF-2α,focusing on their structural and functional similarities and diversities,as well as their roles in the patho-genesis of hypoxic pulmonary hypertension.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Etude d'étiologie
langue:
Chinois
Texte intégral:
Chinese Pharmacological Bulletin
Année:
2017
Type:
Article
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