Application of 13 High-risk HPV infection Test Combined with Thinprep Cytologic Test on Screening Cervical Carcinoma in Dali Region, Yunnan Province / 昆明医科大学学报
Journal of Kunming Medical University
;
(12): 26-29, 2016.
Article
Dans Chinois
| WPRIM
| ID: wpr-510813
ABSTRACT
Objective To investigate relativity between the epidemiology of HPV and cervical carcinoma in Dali region,Yunnan province,through detecting the 13 high-risk human papillomavirus infection and Thinprep cytologic test in 2153 cases.Methods Real-time PCR was used to detect the 13 high-risk HPV (16,18,31,33,35,39,45,51,52,56,58,59,68) in2153 cases and 1604 cases were checked with Thinprep cytologic test.Results In 2153 samples,260 cases were infected with HPV,with the positive rate of 12.08%.The highest positive rates were >60 years old (18.18%),then >20 and ≤30 years old (14.41%);there was no significant difference in the positive rate among the various age groups (P =0.384).There were 1465 negative for intraepithelial lesion ormalignancy (NILM) cases (91.33%),86 atypical squamous cells of undetermined significance (ASC-US) and atypical squamous cells cannot exclude HSIL (ASC-H) cases (5.36%),32 low-grade squamous intraepithelial lesion cases (LSIL) cases (2.00%),21 high-grade squamous intraepithelial lesion cases (1.31%) through Thinprep cytologic test.The correlation coefficient is 0.893.Conclusions The infection rate of HPV in Dali region,Yunnan Province,has no significant difference among the various age groups.Application of 13 high-risk HPV infection test combined with Thinprep cytologic test could be more effective in screening cervical carcinoma.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
/
Étude de dépistage
langue:
Chinois
Texte intégral:
Journal of Kunming Medical University
Année:
2016
Type:
Article
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