Effect of povidone iodine combined with antifungal drugs in the treatment of fungal keratitis / 中国生化药物杂志

ABSTRACT

Objective To analyze the effect of combined use of povidone iodine and antifungal drugs in the treatment of fungal keratitis.Methods 96 cases of fungal keratitis patients suffering from the disease as the research object from March 2014 to March 2016 in our hospital,according to different treatment methods,they were divided into observation group and control group,48 cases in each group,control group received povidone iodine topical treatment,the observation group used povidone iodine and topical antifungal agents the treatment,the clinical efficacy of the two groups received.Results The total efficiency of the observation group was 97.9％higher than that of the control group 85.4％,the difference was statistically significant(χ2=4.909,P0.05 share of the observation group was significantly higher than the control group,the difference was statistically significant(χ2=6.042,P< 0.05); There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion The combined use of povidone iodine and antifungal drugs in the treatment of fungal keratitis can produce a very significant therapeutic effect,effectively improve the visual acuity of patients,and has high application value.