Current status and advances in clinical diagnosis and treatment of mucosal melanoma of the head and neck / 中华放射肿瘤学杂志

ABSTRACT

Mucosal melanoma of the head and neck (MMHN) is a rare malignancy.The sinonasal cavity and oral cavity are the most common primary sites.MMHN is a very aggressive malignant tumor,with the 5-year overall survival (OS) rate less than 30％.Currently,the optimal treatment modality remains unclear.In the najority of available retrospective studies,postoperative radiotherapy improves the local control of MMHN,but without significant effect on OS.This article aims to improve our understanding of the clinical features,diagnosis,staging,treatment modalities,and outcomes of this malignancy.