Cell Transformation Test of Vanadium (V) and Zirconium (Zr) in Yunnan Tin Mine Dust / 昆明医科大学学报

ABSTRACT

There is a high incidence of lung cancer among the miners of Yunnan Tin Mine. We have successfully induced lung cancer in hamsters separately by mine powder, mine powder plus radon or flue dust of the refinery. There are more than thirty similar chemical elements in both mine and flue dust. In order to exclude the action of the trace radioactive chemical elements and to confirm the carcinogenic effect of the non-radioactive inorganic chemical substances, We choose vanadium (V) and zirconium (Zr) to carry out cell transformation test in vitro. The results are as follows 1. The cell toxicity test of V and Zr is positive.2. The cell transformation test of V shows positive and that of Zr is negative. This is reported for the first time.