Behamioral Change and Memory Inpairment Following Transient Forebrain Ischemia in Rats / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 925-930, 1991.
Article
Dans Coréen
| WPRIM
| ID: wpr-51675
ABSTRACT
This study examined the behavioral change and memory impairment following transient forebrain ischemia in 20 male rats ten rats were subjected to sham operation. Inchemia was induced by a combination of bilateral common carotid artery occlusion and induced hypotension. During the recovery period, behavioral change was evaluated by open-field method. Histopathological examination was performed 7 days after ischemic insult. The results were as follows 1) Hippocampus CA 1 neuron was the most vulnerable to 10-minute forebrain ischemia. 2) There was increase in locomotor activity and rearing during early post-ischemic period. 3) Ischemia resulted in suppressed preening and grooming. From the above mentioned results, authors suggested that transient forebrain ischemia produced severe neuronal damage in CA l sector of hippocampus, therefore produced behavioral change and memory impairment.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Prosencéphale
/
Artère carotide commune
/
Soins du pelage
/
Hippocampe
/
Hypotension artérielle
/
Ischémie
/
Mémoire
/
Activité motrice
/
Neurones
Limites du sujet:
Animaux
/
Humains
/
Mâle
langue:
Coréen
Texte intégral:
Korean Journal of Anesthesiology
Année:
1991
Type:
Article
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