The Inhibitory Effect of Dihydro-?-erythroidine on Nicotine Induced-current in Cultured Sympathetic Neurons / 中国药房
China Pharmacy
; (12)1991.
Article
de Zh
| WPRIM
| ID: wpr-517420
Bibliothèque responsable:
WPRO
ABSTRACT
AIM:To investigate the inhibitory effect of dihydro-?-erythroidine on nicotine induced-current in cultured superior cervical ganglion of neonatal rats.METHODS:Pneumatic pressure administration of drug and whole-cell recording techniques were performed to compare induced-current amplitude.RESULTS:Dihydro-?-erythroidine competitively antagonized nicotinic effect,and EC50 was about 0.015mmol/L.CONCLUSION:Dihydro-?-erythroidine is a competitive antagonist of nicotinic receptors in sympathetic neurons.
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WPRIM
langue:
Zh
Texte intégral:
China Pharmacy
Année:
1991
Type:
Article