Expression of intercellular adhesion molecule in lung tissues of experimental acute lung injury and the effect of rhubarb / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1986.
Article
Dans Chinois
| WPRIM
| ID: wpr-517630
ABSTRACT
AIM:
To approach the relationship between the expression of intercellular adhesion (ICAM-1 mRNA) and acute lung injury (ALI) as well as the mechanisms of rhubarb in the prevention and treatment of the lung injury.METHODS:
ALI animal model was performed by Lipopolysaccharide (LPS). The rats were divided into 4 groups LPS group, control group, rhubarb+LPS group and dexamethasone+LPS group. Histopathological examination and biological markers were measured for the lung specimens. Molecular hybridization method was used to determine the expression of ICAM-1 mRNA.RESULTS:
The ICAM-1 mRNA expression in the lung tissues of LPS group significantly increased compared with control group ( P
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Pathophysiology
Année:
1986
Type:
Article
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