Genetic polymorphism of human glutathione S-transferase P1 gene among the Han nationality in Guangdong province / 中国病理生理杂志

ABSTRACT

AIM: To analyse the frequencies of individuals of the GSTP1 genotypes among the Han nationality in Guangdong province. METHODS: Polymerase chain reaction-restriction fragment length polymorphism was taken to analyse the GSTP1 genotypes and identify the gene frequencies. RESULTS: The proportion of AA(Ile/Ile),AG(Ile/Val) and GG(Val/Val) genotypes were 57 4%,35 9% and 6 7%, respectively. CONCLUSION: The frequencies of individuals carrying homozygous of the GSTP1 variant allele were 6.7% among the Han nationality in Guangdong province.