Modification of enzymatic antioxidants in bovine retinal capillary pericytes by advanced glycation end products / 中华眼底病杂志
Chinese Journal of Ocular Fundus Diseases
;
(6)1999.
Article
Dans Chinois
| WPRIM
| ID: wpr-519151
ABSTRACT
Objective To investigate the effect of advanced glycation end products (AGEs) on the catalase activity and the levels of malondialdehyde in cultured bovine retinal capillary pericytes (BRPs), and to investigate the relationship between oxidative stress and diabetic retinopathy. Methods Cultured BRPs were exposed to AGEs (0, 8, 32, 125, 500, 2 000 ?g/ml) for four days. Activity and the levels of catalase and malondialdehyde in cultured BRPs were examined by spectrophotometry. Results AGEs decreased the catalase activity, whereas increased the levels of malondialdehyde of cultured BRPs in a dose dependent manner ( r=-0.714, r=0.748, P
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Ocular Fundus Diseases
Année:
1999
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS