The Influence on the Maternal and Neonatal Outcome by the Type Ⅲ Antibody of Group B Streptococcus / 中华围产医学杂志

ABSTRACT

Objective To learn the influence on the outcome of the pregnant by measuring the type Ⅲ antibody of Group B Streptococcus(GBS). Methods During December 31, 1997 to December 31, 2000, 28 pregnant women whose GBS screening were positive were selected as study group while 46 negative as control group. Vaginal swab cultures were conducted in 74 pregnant women at different gestational periods(before 20 gestational weeks, 20~28 weeks and after 34 weeks). After birth maternal and cord blood samples were collected immediately for the test of GBS IgG antibody with ELISA method. Results 28 of 74 women(37.8%)were GBS culture positive in the antenatal screening. The obstetrical complications such as gestational diabetes millitus, impaired glucose tolerance test, fetal growth retardation, premature rupture of membrane, threatened premature labor and asphyxia of newborn have no significant difference between the GBS carrier group and non-carrier group. The result was same for the newborns. The antibody(IgG)of GBS value of the 74 pairs of maternal and cord blood samples showed that the values of IgG in maternal blood samples and cord blood samples were (3.1?2.2) mg/L and (2.3?1.8) mg/L, respectively,r=0.86,P