Preparation of Inclusion Complex of Diclofenac Sodium-?-Cyclodextrin Eyedrops / 中国药房
China Pharmacy
; (12)2001.
Article
de Zh
| WPRIM
| ID: wpr-520059
Bibliothèque responsable:
WPRO
ABSTRACT
OBJECTIVE:To establish the preparation process of inclusion complex of diclofenac sodium-?-cyclodextrin (DS-?-CD) eyedrops METHODS:The DS-?-CD was prepared by the stir method and identified with instrumental method The content of diclofenac sodium was detected by UV,HPLC RESULTS:The inclusion ratio of DS-?-CD was(67 48?2 96)% There was no difference between diclofenac sodium and DS-?-CD in UV absorption spectrum The crystal diffraction peak of DS inclosed in DS-?-CD disappeared in X-ray CONCLUSION:The DS-?-CD can be used as eyedrops in clinical practice
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
China Pharmacy
Année:
2001
Type:
Article