Dynamic changes of coagulation indexes in the rabbit's amniotic fluid embolism / 中国法医学杂志

ABSTRACT

Objective To observe the dynamic changes in plasma coagulation indexes in the rabbit's amniotic fluid embolism. Method The experimental amniotic embolism model was established by injecting the amniotic fluid or placental extract-amniotic fluid through the rabbit's marginal vein of the ear. Blood samples were taken from the heart before and after infusion. Fibrinogen (FIB), prothrombin time (PT), thrombin time (TT), and activated partial thromboplastin time (APTT) were measured with coagulation analyzer. Results As compared with the sham operation group, FIB decrease significantly after infusion with amniotic fluid and placenta! extract mixed with amniotic fluid (P