The Practical Value of Serum Prealbumin and Butyrylcholinesterase in Child-Pugh Classification of Liver Cirrhosis / 中国医师杂志

ABSTRACT

Objective To study the practical value of serum prealbumin and butyrylcholinesterase in Child-Pugh classification of liver cirrhosis. Methods 66 serum samples of patients with liver cirrhosis and 50 serum samples of the healthy subjects were collected for detecting prealbumin (PA) level and butyrylcholinesterase (BuChE) activity, as well as hepatic functional indices(serum albumin, total bilirubin and alanine aminotransferase). The patients were classified according to the Child-Pugh score. Results Compared with healthy subjects, the content of PA and the activity of BuChE significantly decreased in the patients with liver cirrhosis. According to the Child-Pugh classification, PA content and BuChE activity in different grades of liver cirrhosis varied obviously. Conclusion The content of serum PA and the activity of serum BuChE had an important guiding significance in diagnosing the extent of liver cirrhosis, which can serve as effective indices for diagnosis of patients'condition and prognostic evaluation of liver cirrhosis.