The Factors Affecting the Collection of Allogenic Peripheral Blood Stem Cells in Donors / 中国医师杂志
Journal of Chinese Physician
;
(12)2001.
Article
Dans Chinois
| WPRIM
| ID: wpr-523442
ABSTRACT
Objective To explore the factors affecting the collection of allogenic peripheral blood stem cells in donors. Methods Using COBE-spectra blood cell separator to collect peripheral blood stem cells in 21 allogenic donors. The impact of the factors including the number of white blood cell(WBC) and nucleated cell(NC), and mono-nucleated cell(MNC) ratio on the collecting rate of peripheral blood stem cells was analyzed before and after collection. The output of CD 34 +stem cells stimulated by different doses of G-CSF was also analyzed. Results When the mean count of peripheral WBC and MMC in donors was (41?7.7)?10 9/L and 12?2.9% respectively, the count of collected NC was 2.7?0.8?10 8/L, and the number of the collected CD 34 + stem cells was also higher. Statistical analysis showed that the number of NC was significantly related to the collecting rate of CD 34 stem cells(P
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Journal of Chinese Physician
Année:
2001
Type:
Article
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