Identification of Metronidazole Tablets by Infrared Spectrophotometry / 中国药房

ABSTRACT

OBEJECTIVE:To establish a rapid and exclusive method for the identification of metronidazole tablets.METHODS:The infrared spectrophotometry was adopted,in which the recrystallization was carried out with the dehydrated alcohol as the solvent and with the highly pure potassium bromide tabletting as the infrared absorption spectrum.RESULTS:The infrared absorption spectrum of the metronidazole tablets was completely in conformity with that of the control substance and the standard spectrum of metronidazole issued in Infrared Spectrum Album of Drugs by State Pharmacopoeia Committee.CONCLUSION:This method is specific,fast and accurate,which can be used for the identification of metronidazole prepa-rations.