Expression of transforming growth factor-?1 and its type Ⅰ receptor in autogenous vein grafts in rats / 中国普通外科杂志
Chinese Journal of General Surgery
;
(12)1994.
Article
Dans Chinois
| WPRIM
| ID: wpr-524815
ABSTRACT
ObjectiveTo investigate the expression of TGF ?1 and type Ⅰ receptor and their relations with intimal hyperplasia in autogenous vein grafts in rats. Methods Autogenous vein graft model was established in 48 Wistar rats. The vein grafts were harvested on day 3, 7, 14, and 28.Histomorphological methods were used to measure the thickness of intima and wall at different time points. Immunohistochemistry and Western blot were used to detect the protein expression of TGF ?1 and TGF ?RⅠ . RT PCR was used to detect their mRNA level. ResultsThe intimal thickness increased on day 7 compared with controls( P
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of General Surgery
Année:
1994
Type:
Article
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