Influence of laminin on the expression of bcl-2 in rabbit cornea endothelial cells / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1989.
Article
Dans Chinois
| WPRIM
| ID: wpr-525137
ABSTRACT
AIM:
To investigate the influence of laminin (LN) on the expression of bcl-2 in rabbit cornea endothelial cells.METHODS:
Cultured rabbit corneal endothelial cells were divided into three groups normal control group, LN group and negative control group. Immunohistochemical technique and ELISA were used to measure the staining and A value to assess the levels of bcl-2 expression.RESULTS:
Bcl-2 expression score showed that LN group had a strong positive expression. Control group only showed a weak expression. Negative control group showed a negative expression by immunohistochemical staining. The mean A value of each group were 1.21?0.18 (LN group), 1.05?0.14 (normal control group) and 0.04?0.01 (negative control group).CONCLUSION:
LN promotes bcl-2 gene expression in rabbit cornea endothelial cells, and protects the cells from apoptosis.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Pathophysiology
Année:
1989
Type:
Article
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