Effects of Chlamydia pneumoniae infection and hyperlipidemia on the expression of NF-?B and AP-1 in myocardium / 中国病理生理杂志
Chinese Journal of Pathophysiology
; (12)1999.
Article
Dans Zh
| WPRIM
| ID: wpr-525786
Responsable en Bibliothèque :
WPRO
ABSTRACT
AIM: To investigate the effects of Chlamydia pneumoniae infection and hyperlipidemia on the expression of NF-?B and AP-1 in the myocardium. METHODS: The indirect immunofluorescence method was used to examine wild C57BL/6J mice infected with Chlamydia pneumoniae and fed with an atherogenic diet. The expression of the subunit of NF-?B, P50, and c-Fos in the murine myocardium was observed. RESULTS: Chlamydia pneumoniae infection and hyperlipidemia induced the activation of NF-?B and AP-1 in murine myocardium. P50 and c-Fos were not detected in the controls, but there were different levels of positive expression in the experiments (P
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Journal of Pathophysiology
Année:
1999
Type:
Article