Optimization of Base Material Compositions of Compound Ciprofloxacin Gel by Orthogonal Test and Its Preparation Technology / 中国药房
China Pharmacy
; (12)2005.
Article
Dans Zh
| WPRIM
| ID: wpr-525842
Responsable en Bibliothèque :
WPRO
ABSTRACT
OBJECTIVE:To optimize base material compositions and preparation technology for compound ciprofloxacin gel.METHODS:4factors,ciprofloxacin,carbomer-940,glycerine,triethanolamine(in formula dosages)were selected as variable factors,the stability of the preparation was taken as the index for investigation and table L 9 (3 4 )was used to conduct the orthogonal experiment.RESULTS:The optimum base material composition and technology were the following,ciprofloxacin0.3%,carbomer-9401%,glycerine7.5%,triethanolamine2%.CONCLUSION:The compound ciprofloxacin gel prepared based on the optimized technology is in conformity with the specification stated in Chinese Pharmacopoeia(2000).
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Indice:
WPRIM
langue:
Zh
Texte intégral:
China Pharmacy
Année:
2005
Type:
Article