Diagnosis, management and pregnancy outcomes of twin-twin transfusion syndrome / 中华围产医学杂志

ABSTRACT

Objective To investigate the diagnosis, treatment and pregnancy outcomes of twin-twin transfusion syndrome(TTTS). Methods Eighteen cases of TTTS(TTTS group) were studied retrospectively from Jan 1991 to Oct 2005 in our hospital, and 620 twin pregnancies unaffected by TTTS (control group) were compared. Results (1)The overall incidence of TTTS was 2.8% in all twin pregnancies, and 8.1% in monochorionic twin pregnancies. (2) Fourteen cases of TTTS were staged, and 10 were terminated. Seven cases opted to be managed (1 case at stage Ⅱ, 5 at stage Ⅲ and 1 at stage Ⅳ). Transabdominal amnioreduction was performed in 3 cases, 2 of them progressed to stage Ⅴ and was terminated. One case was treated by fetoscopic laser coagulation and 2 neonates survived.(3)The ratio of conception by assisted reproductive techniques in TTTS group was lower(11.1% vs 40.0%,P