Effects of pregnancy on blood/gas and tissue/gas partition coefficients of fluorinated volatile anesthetics in rats / 中华麻醉学杂志
Chinese Journal of Anesthesiology
; (12)1994.
Article
de Zh
| WPRIM
| ID: wpr-527939
Bibliothèque responsable:
WPRO
ABSTRACT
Objective To determine blood/gas and tissue/gas partition coefficients of sevoflurane, isoflurane and halothane and evaluate the effects of pregnancy on them. Methods Ten 18-22 day pregnant and 10 non-pregnant SD rats were killed under pentobarbital anesthesia. The tissue specimens of heart, liver, kidney and brain were obtained and made into homogenates respectively. The blood/gas and tissue/gas partition coefficients of sevoflurane, isoflurane and halothane were determined using a method of 2-stage headspace equilibration by gas chromatography. Results Blood/gas and brain/gas partition coefficients were lower in pregnant group than in non-pregnant group (P
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Journal of Anesthesiology
Année:
1994
Type:
Article