Effect of Ibudilast on the quality of life of patients with steroid resistant allergic rhinitis:a randomized,double blind,controlled study / 中国耳鼻咽喉头颈外科
Article
Dans Zh
| WPRIM
| ID: wpr-531446
Responsable en Bibliothèque :
WPRO
ABSTRACT
OBJECTIVE To assess the effect of Ibudilast on the quality of life (QOL) of patients with steroid resistant allergic rhinitis.METHODS A randomized,double-blind,placebo-controlled study was carried out with Ibudilast in 66 patients with the steroid resistant allergic rhinitis.QOL was measured with Short-Form Health Survey (SF-36) questionnaire (Chinese version).Ibudilast (10rag twice daily,34 patients),placebo (32 patients) was given for 3 weeks. The SF-36 questionnaire was administered at the start of treatment and after 3 weeks of treatment.Sings and Symptom-medication scores were measured daily during the study.RESULTS There were no significant differences between the Ibudilast and placebo group in terms of sings and symptoms or QOL scores before study.After 3 weeks of treatment,symptoms scores were significantly decreased and QOL scores significantly improved in the Ibudilast group compared with those in placebo group (both P
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Clinical_trials
langue:
Zh
Texte intégral:
Chinese Archives of Otolaryngology-Head and Neck Surgery
Année:
2006
Type:
Article