Quality Standard of Tongtong Granule / 中国药房

ABSTRACT

OBJECTIVE: To establish the quality standard of Tongtong granule. METHODS: Panax notoginseng,Ginkgo biloba and Pueraria lobata were identified qualitatively by TLC and the content of total flavonol glyconsides in G. biloba was determined by HPLC. RESULTS: The TLC spots were distinctive and specific. The linear range of quercetin, kaempferide, isorhamnetin were 5.24～83.84 ?g?mL-1(r=0.999 2), 4.56～72.96 ?g?mL-1(r=0.999 1) and 2.48～39.68 ?g?mL-1(r=0.999 4), respectively. The average recoveries were 96.21%(RSD=2.06%)、99.14%(RSD=1.19%)、95.00%(RSD=1.31%),respectively. CONCLUSION:The method is reliable, accurate, and reproducible for the quality control of Tongtong granule.