Therapeutic Effects of Huangqi Injection in the Treatment of Periodontitis in Rats / 中国药房

ABSTRACT

OBJECTIVE:To investigate the therapeutic effect of Huangqi injection in the treatment of periodontitis in rats.METHODS:Periodontitis model was induced by exposing and lacerating,supplying a high-glucose diet.They were given 8.0 g?kg-1 Huangqi injection for 10 days.Therapeutic effect was evaluated with blood biochemical index and clinical index.RESULTS:Huangqi injection could decrease the level of leukocytes and neutrophils in periodontitis rats while had no effect on erythrocyte,platelet and hemoglobin.Huangqi injection could decrease the level of plaque index (PLI),bleeding index (BI),alveolar bone loss (ABL) and tooth mobility (TM) while had no significant effect on probing depth (PD),periodontal bone support (PBS) and periodontal bone loss (PBL).CONCLUSION:Huangqi injection has therapeutic effect on periodontitis in rats.