Dissolution Determination of Benidipine Hydrochloride Tablets / 中国药房
China Pharmacy
;
(12)2007.
Article
Dans Chinois
| WPRIM
| ID: wpr-534256
ABSTRACT
OBJECTIVE:
To establish a method for the dissolution determination of Benidipine hydrochloride tablets.METHODS:
According to Chinese Pharmacopeia(2005 edition),Benidipine hydrochloride tablets were added into hydrochloride acid 0.1 mo?lL-1 at rotation speed of 50 r?min-1,then samples were obtained after 30 min.The absorbance of samples was detected at detection wavelength of 359 nm and accumulative dissolution was calculated.RESULTS:
The linear range of benidipine hydrochloride was 5~30?g?mL-1(r=0.999 9)with an average recovery of 99.76%(RSD=0.47%).The accumulative dissolutions of 3 batches of samples were all above 80%.CONCLUSIONS:
Established method is simple and reliable for the dissolution determina-tion of Benidipine hydrochloride tablets.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
China Pharmacy
Année:
2007
Type:
Article
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