PANCREATIC POLYPEPTIDE SECRETION IN SIMPLE OBESITY AND TYPE II DIABETES MELLITUS / 中华内分泌代谢杂志

ABSTRACT

Using pancreatic polypeptide (PP) RIA kit prepared in our laboratory, serum levels of PP were observed in obese, type II diabetics with or without insulin treatment and 18 normal controls. The results showed that obese subjects presented hypersecretion of PP, hyperinsulinemia and hyperglycemia. Diabetics presented hypersecretion of PP with low levels of insulin and G-peptide. Possible explanations for hypersecretion of PP were commented.