Study on the changes of arterial blood gas criteria in animals with acute pulmonary oedema due to intoxicated with nitrogen oxides

ABSTRACT

In this study, 35 rabbits were divided into 2 groups: group A included 15 rabbits, that were intoxicated with nitrogen oxide at dose 274.48 mg/m3 of the air; and group B included 20 rabbits that were intoxicated at dose 203.04 mg/m3. Results: all of rabbits in group A died from acute pulmonary edema; PaO2 strong decreased after intoxication, CtO2 decreased at 8 hours after intoxication, PaCO2 and t.CO2 in arterial blood increased. In group B, 55% of rabbits died after intoxication, and the changes of blood gas measurements were similar to those in group A. However, these measurements in survival rabbits were decreased after 24h and then increased at 48h after intoxication