Expression of the Bcl-2 and Bax mRNA in eosihophils of BALF in guinea pig with asthma / 中国免疫学杂志
Chinese Journal of Immunology
;
(12)2000.
Article
Dans Chinois
| WPRIM
| ID: wpr-537173
ABSTRACT
Objective:
To investigate the relation between expression of Bcl-2,Bax and eosinophils(Eos) apoptosis,explore effect of Bcl-2 and Bax on asthma.Methods:
Guinea pigs were divided into normal and asthmatic group randomly. Ovalbumin was used to prepare model of asthma in guinea pig. Apoptosis of Eos in BALF was detected.mRNA expression of Bcl-2 and Bax in Eos were measured by hybridization and RT-PCR.Results:
Comparing with normal group,Eos in BALF from asthmatic group were significantly higher; the percentage of apoptotic Eos from asthmatic group were significantly lower( P
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Immunology
Année:
2000
Type:
Article
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