Changes on cognitive function, brain magnetic resonance imaging and diffusion tensor imaging in patients with multiple sclerosis / 中华神经科杂志

ABSTRACT

Objective To investigate the association of cognitive impairment with the brain structure changes in multiple sclerosis (MS). Methods 70 patients with MS were tested with the Wechsler Intelligence Scale and brain MRI. Analysis was performed to the brain MRI in 50 patients and diffusion tensor imaging (DTI) in 7 patients. Results The rate of the patients whose full intelligence quotient (FIQ) were less than 90 scores was 40% (28/70), which were higher than that of the normal group (P