The Effect of Pretransplantation Dialysis Modality on Long-term Recipient and Graft Survival in Living Donor Kidney Transplantation / 대한신장학회잡지
Korean Journal of Nephrology
;
: 439-446, 2006.
Article
Dans Coréen
| WPRIM
| ID: wpr-53970
ABSTRACT
PURPOSE:
There is increasing consideration about the preemptive transplantation, transplantation without any preceding dialysis, as a one of options of a renal replacement therapy (RRT). This study evaluates a beneficial effect on recipient and allograft survival of preemptive transplantation and compares the outcome to that according to the dialysis modality and duration.METHODS:
All patient who had received a kidney transplant from a living donor in the Seoul National University Hospital (SNUH) between January 1990 and October 2004 are included in this retrospective study. Patients were subdivided into three groups; preemptive transplant group (group 1, n=47), hemodialysis group (group 2, n=307) and peritoneal dialysis group (group 3, n=52).RESULTS:
The characteristics of each groups were not statistically different except recipient age. Ten-year patient survival was 97.8% in PE group, but is not significantly higher than in HD (89.4%) and in PD (90.7%) groups. However, 10-year graft survival was higher in PE group than in HD group (p<0.05; 100%, 74.7% respectively). The differential effect of pretransplant dialysis duration on graft survival was prominent if the patients had been on the pretransplant dialysis for more than 42 months (p<0.05; 10-year graft survival; PE, 100% and dialysis more than 42 months, 77.9% respectively) Compared with HD group as a pre-transplant dialysis modality, PD group showed better patient and graft survival rate, but not statistically significant.CONCLUSION:
Depending on the above results, we may suggest PE or PD being a superior pre-transplant modality than HD. And we should be considerate of choosing treatment modality and duration before transplantation.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Études rétrospectives
/
Dialyse rénale
/
Transplantation rénale
/
Dialyse péritonéale
/
Traitement substitutif de l'insuffisance rénale
/
Donneur vivant
/
Transplants
/
Dialyse
/
Allogreffes
/
Séoul
Type d'étude:
Étude observationnelle
Limites du sujet:
Humains
Pays comme sujet:
Asie
langue:
Coréen
Texte intégral:
Korean Journal of Nephrology
Année:
2006
Type:
Article
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