Effects on structure of mandibles and femurs in ovariectomized rats / 西安交通大学学报(医学版)

ABSTRACT

Objective To investigate the effects on structure of madibles and femurs in ovariectomized rats. Methods Ovariectomy was performed on female SD rats, which were killed 8 weeks later. The mandibles and femurs were taken out as samples to be analyzed by bone histomorphometry and to calculate trabecular area(Tb.Ar), trabecular width(Tb.Wi), trabecular separation(Tb.Sp). Results After ovariectomy the osteopotic trabecular changes had occured in the mandibles and femurs of the rats. There was a significant difference between Tb.Ar, Tb.Wi and Tb.Sp of the mandibles and femurs in ovariectomized rats and sham-ovariectomized(P