The preliminary study on the expression of estrogen receptor ? and ? in temporomandibular joints of Sprague-Dawley rats / 实用口腔医学杂志
Journal of Practical Stomatology
; (6)1996.
Article
de Zh
| WPRIM
| ID: wpr-542835
Bibliothèque responsable:
WPRO
ABSTRACT
Objective:To investigate the expression of estrogen receptor ? and ?(ER? and ER?) in temporomandibular joints(TMJs) of Sprague-Dawley rats.Methods:The expression of ER? and ER? in TMJs was examined by SABC technique of immunocytochemistry, meanwhile the co-expression of them was detected by double-staining technique of immunocytochemistry.Results:①Intense ER? and ER? immunoreactivity was localized in the hypertrophic layer of condyle cartilage,and some immunoreactivity was found in osteocytes of mandible and temporal bone. ②The immunoreactivity of ER? and ER? was found in both nuclei and cytoplasms. Most of immunoreactivity of ER? was localized in nuclei, while ER? was distrubuted more evenly. ③The expression of ER? was wider than that of ER?.Conclusions:TMJ is one of target organs of estrogen.The expression of ER? is different from that of ER?,which suggests there may be different mechanisms directed by ERs.
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Journal of Practical Stomatology
Année:
1996
Type:
Article