Estrogen receptor expression in genioglossus of ovariectomized rats / 实用口腔医学杂志

ABSTRACT

Objective:To investigate the expression of estrogen receptor in genioglossus of female rats. Methods:30 female Sprague-Dawley rats were randomly assigned to three groups normal group(NORMAL), sham operation group (SHAM) and ovariectomized group(OVX). The rats were sacrificed 6 weeks after surgery, and the genioglossus was removed for analysis. The expression of estrogen receptors(ER? and ER?) was examined by immunohistochemical assay. Results:ER? and ER? were found in genioglossus of normal rats. The expression of ER? was significantly higher than ER? (P0.05). Conclusions:Estrogen receptors are expressed in genioglossus of female rats.ER? expression is significantly impacted by the estrogen level.