Effect of combined treatment of glargine and gllpizide GITS on metabolic control and ?-cell function / 中华内分泌代谢杂志

ABSTRACT

Diabetic patients with secondary sulfonylureas failure were shifted to glipizide plus glargine ( n = 20) or neutral protamine hagedorn (n =32). Sixteen weeks later, blood glucose and HbAIC were decreased and serum C peptide level increased in both groups. Hypoglycemia occurred less frequently and?-cell function was improved in glargine group.