The relationship of interleukin-4 and interferon-? with steroid effect in children with primary nephrotic syndrome / 西安交通大学学报(医学版)
Article
de Zh
| WPRIM
| ID: wpr-544039
Bibliothèque responsable:
WPRO
ABSTRACT
Objective To study the relationship between the activity of interleukin-4 and interferon-? with steroid effect in children with primary nephrotic syndrome before initiation of steroid therapy. Methods The activity of interleukin-4 and interferon-? in the supernatants of monocytes cell cultures activated with phytohemagglutinin was assessed with enzyme-linked immunosorbentassay in 31 children with primary nephrotic syndrome before iniatiation of steroid therapy. After steroid treatment for 8 weeks, data of steroid sensitivity and resistance were analyzed. Results Before initiation of steroid treament, in steroid sensitivity children with primary nephrotic syndrome an increased proliferative response of interleukin-4 was found (P0.05). Conclusion The activity of interleukin-4 is a useful tool for evaluating the likelihood of steroid sensitivity in children with primary nephrotic syndrome.
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Journal of Xi'an Jiaotong University(Medical Sciences)
Année:
2004
Type:
Article