Expression level of osteopotin and lupus nephritis / 中国免疫学杂志
Chinese Journal of Immunology
;
(12)1985.
Article
Dans Chinois
| WPRIM
| ID: wpr-546061
ABSTRACT
Objective:
To explore the role of osteopotin in lupus nephritis (LN).Methods:
Sera osteopotin( OPN )levels were measured by enzyme linked immunosorbent assay in 90 patients with systemic lupus erythematosus (SLE),15 non-SLE patients with renal impairment,and 30 healthy volunteers.OPN mRNA expression in peripheral blood mononuclear cells (PBMCs) was also investigated with reverse transcription-polymerase chain reaction semi-quantitative method.Results:
The expression of OPN was significantly higher in active LN groups than in all other groups(P0.05).Conclusion:
The expression of PBMCs OPN mRNA is up regulation in active SLE.Meanwhile,its expression levels are correlated with the activity of LN.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Immunology
Année:
1985
Type:
Article
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