Physiologically Based Pharmacokinetic Models for Use in Risk Assessment of Xylene / 环境与健康杂志
Journal of Environment and Health
;
(12)1992.
Article
Dans Chinois
| WPRIM
| ID: wpr-546277
ABSTRACT
As a mature tool for estimating tissue dosimetry,physiologically based pharmacokinetic (PBPK) models are being used to simulate the process from an external chemical exposure to an internal exposure at a target site,for supporting quantitative predictions of risks to human health. This paper reviewed these models from three aspects the general steps of model construction,the criteria of model evaluation,the use of model in risk assessment and taking xylene as an example particularly described the third aspect.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Etude d'étiologie
/
Étude pronostique
/
Facteurs de risque
langue:
Chinois
Texte intégral:
Journal of Environment and Health
Année:
1992
Type:
Article
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